ncRNA name | TNFα siRNA |
ncRNA Category | siRNA |
Disease name | Behcet's disease (BD) |
Species | Mus musculus |
Tissues/Cell_line | macrophages; serum |
Methods | siRNA transfection and injeciton, RT-PCR, qPCR, ELISA |
Expression pattern | associated |
Functional description | Intraperitoneal delivery of TNFalpha siRNA effectively decreased BD symptoms in 18 of 32 cases. After single injection of TNFalpha siRNA, improvement of BD symptoms showed at 9 +/- 7th day on an average. |
PubMed ID | 18585901 |
Year | 2008 |
Title | Tumor necrosis factor alpha small interfering RNA decreases herpes simplex virus-induced inflammation in a mouse model. |
Drug-related ncRNA | NO |
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