logo

        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of Behcet's disease (BD)
ncRNA name TNFα siRNA
ncRNA Category siRNA
Disease name Behcet's disease (BD)
Species Mus musculus
Tissues/Cell_line macrophages; serum
Methods siRNA transfection and injeciton, RT-PCR, qPCR, ELISA
Expression pattern associated
Functional description Intraperitoneal delivery of TNFalpha siRNA effectively decreased BD symptoms in 18 of 32 cases. After single injection of TNFalpha siRNA, improvement of BD symptoms showed at 9 +/- 7th day on an average.
PubMed ID 18585901
Year 2008
Title Tumor necrosis factor alpha small interfering RNA decreases herpes simplex virus-induced inflammation in a mouse model.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.